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A Note on Age-Related Biomarkers

Institute of Gerontology, King's College London (University of London), and Eye Department, University College London Hospital, United Kingdom.

Address correspondence to Prof. Robert A. Weale, Institute of Gerontology, King's College London (University of London), Waterloo Bridge Wing, Waterloo Rd., London SE1 9NN. E-mail: robert.weale{at}kcl.ac.uk

Forty-eight randomly selected age-related human biological functions were analyzed in order to establish whether or not their (linear) regressions were modified by age-related standard errors. Possible reasons for this are advanced. Statistically significant multiple regressions were obtained in 25%, and 21% of the functions yielded statistically significant changes in the correlations between data and age when partial correlation coefficients were calculated. The conclusion is that age-related data need to be subjected to the above tests in order to minimize confounding factors.