Journals of Gerontology Series A: Biological Sciences and Medical Sciences Large Type Edition
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The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 59:B201-B217 (2004)
© 2004 The Gerontological Society of America

How Are Biomarkers Related to Physical and Mental Well-Being?

Christopher L. Seplaki1,, Noreen Goldman1, Maxine Weinstein2 and Yu-Hsuan Lin3

1 Office of Population Research, Princeton University, New Jersey.
2 Center for Population and Health, Georgetown University, Washington, District of Columbia.
3 Bureau of Health Promotion, Center for Population and Survey Research, Department of Health, Taichung, Taiwan.

Address correspondence to Christopher L. Seplaki, PhD, Office of Population Research, 263 Wallace Hall, Princeton University, Princeton, NJ 08544. E-mail: cseplaki{at}princeton.edu

We investigate how biological markers of individual responses to stressful experiences are associated with profiles of physical and mental functioning in a national sample of middle-aged and elderly Taiwanese. Data come from a population-based sample of middle-aged and elderly Taiwanese in 2000. The data combine rich biological measures with self-reported information on physical and mental health. Grade of membership methods are used to summarize functional status, and multinomial logit models provide information on the association between biological measures and function. The analysis identifies significant associations between biomarkers of stressful experience and profiles of physical and mental functioning. The estimates reveal the potential importance for health of both low and high values of biological parameters. The findings point to directions for future research regarding development of aggregate measures of cumulative dysregulation across multiple physiological systems.


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Erratum

Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2006 61: 209. [Full Text]  





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