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Table 3. Changes in Life Span Relative to Expected Longevity Quotient, and Hormone and Glycated Hemoglobin Concentrations in Natural Rodent Models With Extended Longevity.

Species LQ* Thyroxine (mg/dl) IGF-1 (ng/ml) Glycated Hemoglobin, % Source
Laboratory mice 1 5.0 ± 0.2 591 ± 25 10.2 ± 1.2 Miller et al., 2002
Majuro mice 1.1 2.3 ± 0.1 464 ± 48 20.2 ± 1.0 Miller et al., 2002
Idaho mice 1.2 4.4 ± 0.3 300 ± 27 3.8 ± 0.2 Miller et al., 2002
Naked mole-rats 5.0 0.004 ± 0.001 NAD 5.5 ± 0.3 This study

Note: *Based on allometric equation of Austad and Fisher (4).

LQ = longevity quotient; IGF-1 = insulin-like growth factor-1; NAD = no available data.





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