| HOME | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|---|
| ||||||||||||||||||||||||||||||||
1 Department of Public Health, Oregon State University, Corvallis.
2 Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pennsylvania.
3 Department of Biostatistics, Boston University School of Public Health, Massachusetts.
Departments of 4 Neurology and 5 Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania.
Address correspondence to Hiroko Dodge, PhD, 304 Waldo Hall, Department of Public Health, Oregon State University, Corvallis, OR 97331. E-mail: dodge{at}oregonstate.edu
Background. Cognitive impairment in general is known to predict functional disability, but it is not clear whether performance on specific cognitive domains predicts future disability trends among nondemented elderly persons.
Methods. In a representative elderly community-based cohort over up to 10 years of follow-up, we examined predictors of longitudinal trajectories in ability to perform Instrumental Activities of Daily Living (IADL) among nondemented elderly persons. We used trajectory analyses to identify homogeneous groups with respect to trends over time in the numbers of IADL disabilities and their association with baseline demographics, social engagement, depression, physical well-being, and general and domain-specific cognitive functions. We excluded from these analyses those individuals found to have dementia at baseline or at any time during follow-up.
Results. Trajectory analysis revealed three homogeneous latent groups which we characterized as No Decline (no decline in abilities to perform IADL tasks over the course of study), Moderate Decline (some functional decline), and Sharp Decline (steep functional decline followed by death). Compared to the Sharp Decline group, the No Decline group was associated with higher baseline functions in all cognitive domains, and the Moderate Decline group was associated with higher baseline functions in all cognitive domains except psychomotor speed and naming. The Moderate and No Decline groups did not differ on any cognitive measure.
Conclusion. Among community dwelling elderly persons who remained free from dementia throughout the study, poorer scores in all cognitive domains predicted sharp functional decline followed by death.
This article has been cited by other articles:
 |
|
 |
|
  K. B. Dassel and F. A. Schmitt The Impact of Caregiver Executive Skills on Reports of Patient Functioning Gerontologist, December 1, 2008; 48(6): 781 - 792. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. H. Dodge, Y. Kita, H. Takechi, T. Hayakawa, M. Ganguli, and H. Ueshima Healthy Cognitive Aging and Leisure Activities Among the Oldest Old in Japan: Takashima Study J. Gerontol. A Biol. Sci. Med. Sci., November 1, 2008; 63(11): 1193 - 1200. [Abstract] [Full Text] [PDF]
|
|
| HOME | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|---|
