Journals of Gerontology Series A: Biological Sciences and Medical Sciences Large Type Edition
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Roth, S.M.
Right arrow Articles by Rogers, M.A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Roth, S.M.
Right arrow Articles by Rogers, M.A.
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 56:B240-B247 (2001)
© 2001 The Gerontological Society of America

Skeletal Muscle Satellite Cell Characteristics in Young and Older Men and Women After Heavy Resistance Strength Training

S.M. Rotha, G.F. Martela,b, F.M. Iveya, J.T. Lemmera, B.L. Tracya, E.J. Metterc, B.F. Hurleya and M.A. Rogersa

a Department of Kinesiology, University of Maryland, College Park
b Department of Physical Therapy, University of Maryland Eastern Shore, Princess Anne
c Gerontology Research Center, National Institute on Aging, Baltimore, Maryland

S.M. Roth, A300 Crabtree Hall, Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15261 E-mail: sroth{at}helix.hgen.pitt.edu.

Decision Editor: John A. Faulkner, PhD

Skeletal muscle satellite cell proportions and morphology were assessed in healthy, sedentary young and older men and women in response to heavy resistance strength training (HRST). Fourteen young (20–30 years) men (n = 7) and women (n = 7) and 15 older (65–75 years) men (n = 8) and women (n = 7) completed 9 weeks of unilateral knee extension exercise training 3 days per week. Muscle biopsies were obtained from each vastus lateralis before and after training, with the nondominant leg serving as an untrained control. All four groups demonstrated a significant increase in satellite cell proportion in response to HRST (2.3 ± 0.4% vs 3.1 ± 0.4% for all subjects combined, before and after training, respectively; p < .05), with older women demonstrating the greatest increase (p < .05). Morphology data indicated a significant increase in the proportion of active satellite cells in after-training muscle samples compared with before-training samples and with control leg samples (31% vs 6% and 7%, respectively; p < .05). The present results indicate that the proportion of satellite cells is increased after HRST in young and older men and women, with an exaggerated response in older women. Furthermore, the proportion of satellite cells that appear morphologically active is increased as a result of HRST.




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
D. L. Enns and P. M. Tiidus
Estrogen influences satellite cell activation and proliferation following downhill running in rats
J Appl Physiol, February 1, 2008; 104(2): 347 - 353.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
A. L. Mackey, M. Kjaer, S. Dandanell, K. H. Mikkelsen, L. Holm, S. Dossing, F. Kadi, S. O. Koskinen, C. H. Jensen, H. D. Schroder, et al.
The influence of anti-inflammatory medication on exercise-induced myogenic precursor cell responses in humans
J Appl Physiol, August 1, 2007; 103(2): 425 - 431.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
L. B. Verdijk, R. Koopman, G. Schaart, K. Meijer, H. H. C. M. Savelberg, and L. J. C. van Loon
Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly
Am J Physiol Endocrinol Metab, January 1, 2007; 292(1): E151 - E157.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
J. K. Petrella, J.-s. Kim, J. M. Cross, D. J. Kosek, and M. M. Bamman
Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women
Am J Physiol Endocrinol Metab, November 1, 2006; 291(5): E937 - E946.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
S. Olsen, P. Aagaard, F. Kadi, G. Tufekovic, J. Verney, J. L. Olesen, C. Suetta, and M. Kjaer
Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training
J. Physiol., June 1, 2006; 573(2): 525 - 534.
[Abstract] [Full Text] [PDF]

Home page
 Sci SignalHome page
V. Sartorelli and M. Fulco
Molecular and Cellular Determinants of Skeletal Muscle Atrophy and Hypertrophy
Sci. Signal., August 3, 2004; 2004(244): re11 - re11.
[Abstract] [Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
S. A. Hawkins, R. A. Wiswell, and T. J. Marcell
Exercise and the Master Athlete--A Model of Successful Aging?
J. Gerontol. A Biol. Sci. Med. Sci., November 1, 2003; 58(11): M1009 - 1011.
[Abstract] [Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
J. E. Morley
Editorial: Sarcopenia Revisited
J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2003; 58(10): M909 - 910.
[Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
K. E. Yarasheski
Review Article: Exercise, Aging, and Muscle Protein Metabolism
J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2003; 58(10): M918 - 922.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
All GSA journals The Gerontologist
Journals of Gerontology Series B: Psychological Sciences and Social Sciences
Copyright © 2001 by The Gerontological Society of America.